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Prevalence of Hypothyroidism in PCOS in Jharkhand

Received: 15 January 2022    Accepted: 14 February 2022    Published: 25 February 2022
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Abstract

Polycystic ovarian syndrome and thyroid disorders are common endocrine disorders in females worldwide. These two problems are having many common features but are with very different etiopathogenesis. The increase in ovarian volume and cystic changes in ovaries have been reported in primary hypothyroidism due to disturbed ratio of FSH and LH. It is also seen that thyroid disorders are more common in women with PCOS as compared to the normal population may be due to other associated factors like insulin resistance, increased androgen secretion and obesity. There might be some common factors in individuals predisposing to both disorders but till date not any common pathophysiology is established between these two. The increased ovarian volume and fertility improves by administration of thyroxin apart from that it helps to control obesity and to some extent obesity related disorders. The diagnosis of hypothyroidism during adolescence will be helpful to improve especially fertility and PCOS related clinical conditions. The thyroid function study was done in PCOS patients between 18 to 35 years of age residing in Jharkhand and the results were compared with age matched healthy women. Having no medical problem or on contraceptive steroids females. Serum fasting free t3,free t4 and TSH levels were estimated. PCOS was confirmed by USG. Results of present study shows the prevalence of hypothyroidism in PCOS patient in Jharkhand.

Published in Journal of Family Medicine and Health Care (Volume 8, Issue 1)
DOI 10.11648/j.jfmhc.20220801.13
Page(s) 21-24
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Hypothyroidism, Polycystic Ovaries, Freet3, Freet4

References
[1] Balaji S Amadi C, Prasad S, Bala Kesav J et al. urban rural comparisons of polycystic ovary syndrome burden among adolescent girls in a hospital setting in India. biomed Res Int 2015: 2015: 158951 (PMC free article).
[2] Poison DW, Adams J, Wadsworth J, Franks s: Polycystic ovaries– A common finding in normal women. Lancet 1988; 1: 870-872.
[3] Guzick D. Polycystic ovary syndrome: symptomatology, pathophysiology, and epidemiology. Am J Obstet Gynecol 1998; 179: S89-S93.
[4] Yen SSC. Polycystic ovary syndrome (Hyperandrogenic chronic anovulation) 1999. Philadelphia, W. B. Saunders Company.
[5] Balen AH Hypersecretion of luteinizing hormone and the polycystic ovary syndrome. Hum Reprod 1993; 89 (suppl 2): 123-128.
[6] Abraham R et al. Thyroid disorders in women of Puducherry. Indian J Clin Biochem. 2009 Jan; 24 (1): 52-9.
[7] Unnikrishnan AG, Menon UV. Thyroid disorders in India: An epidemiological perspective. Indian J Endocrinol Me-tab. 2011 Jul; 15 (Suppl 2): S78-81.
[8] Singla R et al Thyroid disorders and polycystic ovavary syndrome Indian J Endocrinal metab. 2015 jan-Feb 19 (1) 25-29.
[9] Sinha U et al Thyroid disorders in polycystic ovarian syndrome subjects. Indian J Endocrinol Metab. 2013; 17: 304–309.
[10] Danfeng D & Xuelian L. The relationship between thyroiditis and PCOS. Int J Clin Exp Med. 2013; 6 (10): 880-9.
[11] Ulrich J et al Impact of Autoimmune thyroiditis on reproductive and metabolic parameters with PCOS; Exp Clin Endocrinal diabetes 2018; 126; 198-24.
[12] K lavanya et al Association of hypothyroidism and PCOS Int J of Clin Bio and research sep 2019; 6 (3) 405-409.
[13] Benetti-Pinto CL et al Subclinical hypothyroidism in young women with PCOS. Fertil Steril. 2013; 99: 588–92.
[14] Muderris II et al Effect of thyroid hormone replacement therapy on ovarian volume and androgen hormones in patients with untreated primary hypothyroidism. Ann Saudi Med. 2011; 31: 145–51.
[15] Kachuei M et al Prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome. Arch Gynecol Obstet. 2012; 285: 853.
Cite This Article
  • APA Style

    Geetanjali Kumari, Ranjit Kaur Arora. (2022). Prevalence of Hypothyroidism in PCOS in Jharkhand. Journal of Family Medicine and Health Care, 8(1), 21-24. https://doi.org/10.11648/j.jfmhc.20220801.13

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    ACS Style

    Geetanjali Kumari; Ranjit Kaur Arora. Prevalence of Hypothyroidism in PCOS in Jharkhand. J. Fam. Med. Health Care 2022, 8(1), 21-24. doi: 10.11648/j.jfmhc.20220801.13

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    AMA Style

    Geetanjali Kumari, Ranjit Kaur Arora. Prevalence of Hypothyroidism in PCOS in Jharkhand. J Fam Med Health Care. 2022;8(1):21-24. doi: 10.11648/j.jfmhc.20220801.13

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  • @article{10.11648/j.jfmhc.20220801.13,
      author = {Geetanjali Kumari and Ranjit Kaur Arora},
      title = {Prevalence of Hypothyroidism in PCOS in Jharkhand},
      journal = {Journal of Family Medicine and Health Care},
      volume = {8},
      number = {1},
      pages = {21-24},
      doi = {10.11648/j.jfmhc.20220801.13},
      url = {https://doi.org/10.11648/j.jfmhc.20220801.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20220801.13},
      abstract = {Polycystic ovarian syndrome and thyroid disorders are common endocrine disorders in females worldwide. These two problems are having many common features but are with very different etiopathogenesis. The increase in ovarian volume and cystic changes in ovaries have been reported in primary hypothyroidism due to disturbed ratio of FSH and LH. It is also seen that thyroid disorders are more common in women with PCOS as compared to the normal population may be due to other associated factors like insulin resistance, increased androgen secretion and obesity. There might be some common factors in individuals predisposing to both disorders but till date not any common pathophysiology is established between these two. The increased ovarian volume and fertility improves by administration of thyroxin apart from that it helps to control obesity and to some extent obesity related disorders. The diagnosis of hypothyroidism during adolescence will be helpful to improve especially fertility and PCOS related clinical conditions. The thyroid function study was done in PCOS patients between 18 to 35 years of age residing in Jharkhand and the results were compared with age matched healthy women. Having no medical problem or on contraceptive steroids females. Serum fasting free t3,free t4 and TSH levels were estimated. PCOS was confirmed by USG. Results of present study shows the prevalence of hypothyroidism in PCOS patient in Jharkhand.},
     year = {2022}
    }
    

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    JO  - Journal of Family Medicine and Health Care
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    AB  - Polycystic ovarian syndrome and thyroid disorders are common endocrine disorders in females worldwide. These two problems are having many common features but are with very different etiopathogenesis. The increase in ovarian volume and cystic changes in ovaries have been reported in primary hypothyroidism due to disturbed ratio of FSH and LH. It is also seen that thyroid disorders are more common in women with PCOS as compared to the normal population may be due to other associated factors like insulin resistance, increased androgen secretion and obesity. There might be some common factors in individuals predisposing to both disorders but till date not any common pathophysiology is established between these two. The increased ovarian volume and fertility improves by administration of thyroxin apart from that it helps to control obesity and to some extent obesity related disorders. The diagnosis of hypothyroidism during adolescence will be helpful to improve especially fertility and PCOS related clinical conditions. The thyroid function study was done in PCOS patients between 18 to 35 years of age residing in Jharkhand and the results were compared with age matched healthy women. Having no medical problem or on contraceptive steroids females. Serum fasting free t3,free t4 and TSH levels were estimated. PCOS was confirmed by USG. Results of present study shows the prevalence of hypothyroidism in PCOS patient in Jharkhand.
    VL  - 8
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Author Information
  • Physiology, Hind Institute of Medical Sciences, Lucknow, India

  • Physiology, Palamu Medical College, Harkhand, India

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